The Global Platelet Aggregation Devices Market Size Is Expected To Reach USD 1,556.8 Million by 2027 according to a new study by Polaris Market Research. Platelet aggregation is the biological process where the platelet cells are employed in a process to prevent bleeding through vaso-constriction for rapid clot formation. The whole process is mediated via platelet aggregating factor (PAF). The quantitative and qualitative defects of platelets lead to increased bleeding. The high reactivity of platelets in the patients having anti-platelet therapy results in thromboembolic complications.
Platelet function related disorders
can be either inherited or acquired. The inherited platelet function disorders
include Von Willebrand disease, Glanzmann’s thrombasthenia, Bernard-Soulier
syndrome, Storage pool disease. The acquired platelet dysfunction may be caused
by chronic conditions such as kidney failure (uremia), Myelodysplastic
syndrome (MDS), Leukemias (chronic myeloid leukemia or CML; acute myeloid
leukemia or AML).
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Some acquired platelet disorders are temporary because of the
decreased function of platelets due to anti-platelet medications, non-steroidal
anti-inflammatory drugs (NSAIDs), tricyclic antidepressants, antihistamines and
some antibiotics. The platelet function testing is transitioned from
diagnostics for heritable diseases to a functional one for platelet functional
therapies. The rapid usage of anti-platelet therapy, mainly dual anti-platelet
therapy has changed the focus of platelet function testing from diagnostics to
therapeutics.
The market is driven by few notable
factors such as the recent surge in infectious diseases (COVID-19) requiring
rapid serological tests, innovations in platelet aggregation mechanisms,
systems and consumables, and worldwide rise in chronic ailments. Specialized
tests based on platelet aggregation include light transmission platelet
aggregometry on platelet-rich plasma (LTA), impedance whole blood aggregometry
(WBA), Lumi-aggregometry and flow cytometry.
Automated haematology analyzers can
be used to obtain platelet counts over a wide range of values using optical
counting methods like light scatter or fluorescence. Screening tests such as
prothrombin time (PT) or activated partial thromboplastin time (aPTT) are more
standardized and fully automated.
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Number of reagents are available in
the market to carry out the platelet function tests. These reagents include
collagen, thrombin, ADP, vasopressin, epinephrine and ristocetin. Collagen, ADP
were used in routine platelet aggregation studies for the evaluation of
qualitative platelet function disorders.
Market participants such as F. Hoffmann
La-Roche Ltd., Drucker Diagnostics, Haemonetics Corporation, Sysmex
Corporation, Siemens Healthineers, Chrono-log Corporation, Instrumentation
Laboratory, Accriva Diagnostics, Matis Medical, Helena Laboratories
Corporation, Sienco, Inc., Bio/Data Corporation, Tem Group, WerfenLife, S.A.,
Laboratory Corporation of America Holdings, Sentinel CH. S.p.A., and Aggredyne,
Inc. are some of the key players operating in the concerned market.
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